The Sheraton Albuquerque Uptown Hotel is located in the uptown business district and is just 7 miles from downtown Albuquerque and Old Town. From Albuquerque International Airport, exit the airport on Sunport Loop SE. Take I-25 North towards downtown. Take Exit #266AB towards Santa Rosa onto I-40 East. Take Exit #162B towards Louisiana Blvd N. Bear right on Louisiana Blvd NE.