The exquisite Palomar Hotel San Francisco is located on fourth and market streets in downtown San Francisco. It is just 2 blocks south of Union Square, the city's principal shopping area, 1 block north of the Yerba Buena Center for the Arts, the San Francisco Museum of Modern Art, the Moscone Convention Center and the new Sony Metreon Center. San Francisco International Airport is only 14 miles away from the hotel.

Direction From San Francisco Airport or San Jose via Highway 101 North : From Highway 101 North, stay in the "Bay Bridge - Interstate 80" lane as you approach San Francisco. Exit at 7th Street (before you get to the bridge). Bear left on 7th Street, which is one-way. Turn right at Market Street. Drive three blocks. Turn right on 4th Street. Palomar Hotel San Francisco is located on the right side of the street.

Direction From the Golden Gate Bridge via Highway 101 South : Cross the Golden Gate Bridge and take the Lombard Street exit. Go 14 blocks on Lombard. Turn right on Van Ness Avenue; go 14 blocks on Van Ness. Turn left on O'Farrell Street. Drive nine blocks on O'Farrell. Turn right on Stockton Street (Crate & Barrel is on the near corner). Drive one block to Market. Cross Market Street; Stockton turns into 4th Street. Palomar Hotel San Francisco is located on the right side of the street.

Direction From the Oakland area via the Bay Bridge and Interstate 80 : Cross the Bay Bridge and take the 5th Street exit. Veer to the right on to 5th Street to Market Street. Turn right on Market Street. Drive one block to 4th Street. Turn right on 4th Street. Palomar Hotel San Francisco is located half a block down on the right side of the street.