From Los Angeles International Airport to Millennium Biltmore Hotel Los Angeles: Start out onto South Sepulveda Boulevard. Exit onto I-105 East and take I-110 towards Los Angeles. Merge onto I-110 North and exit 22-B. Turn right and merge onto West 6th Street. Turn left onto South Olive Street. Turn left onto West 5th Street. Turn left onto South Grand Avenue. Turn left onto West 5th Street Turn left onto South Grand Avenue.
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