Holiday Inn Express Las Vegas Nellis Hotel is conveniently located outside of Nellis Air Force Base at Nellis and Las Vegas Blvd, within 12 miles North of the Las Vegas Strip, about 1 mile West of Nellis AFB and within 4 miles South of the Las Vegas Motor Speedway.

Holiday Inn Express Las Vegas Nellis Hotel is located near Boeing, SAIC, Bechtel, Western States, and Frehner Construction, Sunrise Hospital and North Vista Hospital, North Beltway Business Park and the Raceway Business Park.